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  1. Main
  2. Employees
  3. Ashot S Saghyan
download PDF
34-10
saghyan@ysu.am
Ashot
S
Saghyan
Institute of Pharmacy
Chair of Pharmaceutical Chemistry and Pharmacognosy
Professor

Personal information

Date of birth
1957
Education
Institution
Yerevan State University
Faculty
Faculty of Chemistry
Date
1973 - 1978
Degree name
Qualified specialist
Scientific Rank/degree
Institution
Yerevan State University
Date
2003
Degree name
Professor
Specialty
Chemical sciences
Institution
Yerevan State University
Date
1997
Degree name
Doctor
Specialty
Chemical sciences
Research Topic
Asymmetric synthesis of non-proteinogenic (S)- and (R)- alpha amino acids via chiral dehydroamino acids complex of Co3+ and Ni 2+
Institution
A.N.Nesmeyanov Institute of Organoelement Compounds of Russian Academy of Sciences
Date
1985
Degree name
Postgraduate
Scientific Supervisor
Yu. N Belokon
Research Topic
Synthesis and reactivity of complexes of Schiff bases of dehydroamino acids with Co(III) and Ni(II) ions
Language skills
Русский
English

Publications

- Կատեգորիա -
Article
Biological macromolecule binding and anticancer activity of synthetic alkyne-containing L-phenylalanine derivatives
Marta A. Fik-Jaskółka
Anna F. Mkrtchyan
Ashot S. Saghyan
Rosanna Palumbo
Agnieszka Belter
Liana A. Hayriyan
Hayarpi Simonyan
Valentina Roviello
Giovanni N. Roviello
Amino Acids
2020
755–769
Article
Asymmetric Synthesis of Tailor-Made Amino Acids Using Chiral Ni(II) Complexes of Schiff Bases. An Update of the Recent Literature
Yupiao Zou
Jianlin Han
Ashot S. Saghyan
Anna F. Mkrtchyan
Hiroyuki Konno
Hiroki Moriwaki
Kunisuke Izawa
Vadim A. Soloshonok
Molecules
2020
2739
Article
Using the Ni-[(Benzylprolyl)amino]benzophenone complex in the Glaser reaction for the synthesis of bis α-amino acids
Anna F. Mkrtchyan
Liana A. Hayriyan
Ani J. Karapetyan
Anna S. Tovmasyan
Avetis H. Tsaturyan
Victor N. Khrustalev
Viktor I. Maleev
Ashot S. Saghyan
New Journal of Chemistry
2020
8
Article
Исследование асимметрического нуклеофильного бис-присоеденения дегидроаланиновых комплексов Ni(II)
Петросян С. Г.
Симонян А. М
Мкртчян А. Ф.
Саакян Л. Ю.
Цатурян A. O.
Сагян А. С.
Հայաստանի քիմիական հանդես
2020
213-222
Article
Synthesis of Enantiomerically Enriched Non-Proteinogenic α-Amino Acids Using the Suzuki Reaction
Saghyan Ashot
Mkrtchyan Anna
Mardiyan Zorayr
Hayriyan Liana
Yuri N. Belokon
Peter Langer
ChemistrySelect
2019
4686-4688
Article
Synthesis of enantiomerically enriched alkynylaryl‐substituted α‐amino acids through Sonogashira reactions
Ashot S. Saghyan
Anna F. Mkrtchyan
Zorayr Z. Mardiyan
Liana A. Hayriyan
Ani J. Karapetyan
Yuri N. Belokon
Peter Ehlers
Peter Langer
ChemistrySelect
2019
13806-13809
Article
SYNTHESIS AND PHARMACOLOGICAL ACTIVITY OF S(-)-2-AMINO-2-METHYL-3-PHENYLPROPANOIC ACID
S. H. Grigoryan
A. G. Zhamharyan
A. S. Saghyan
A. A. Chitchiyan
L. S. Balyan
A. S. Poghosyan
H. V. Topchyan
M. G. Balasanyan
Химико-фармацевтический журнал (Pharmaceutical Chemistry Journal)
2019
620-623
Article
SYNTHESIS OF N-TERT-BUTYLOXYCARBONYLGLYCYL-(S)-b-[4- ALLYL-3-PROPYL-5-THIOXO-1,2,4-TRIAZOL-1-YL]--ALANINE DIPEPTIDE AND STUDY OF ITS ANTIFUNGAL EFFECT
T. H. SARGSYAN
Z. Z. MARDIYAN
Yu. M. DANGHYAN
E. A. GYULUMYAN
N. S. KHACHATURYAN
S. A. GEVORGYAN
H.I. HAKOBYAN
S. M. JAMGARYAN
A. S. SAGHYAN
Chemical Journal of Armenia
2019
495-501
Article
СРАВНИТЕЛЬНОЕ ИЗУЧЕНИЕ АНТИОКСИДАНТНОЙ АКТИВНОСТИ β-ГЕТЕРОЦИКЛИЧЕСКИ ЗАМЕЩЕННЫХ АНАЛОГОВ α-АМИНОМАСЛЯНОЙ КИСЛОТЫ И НЕКОТОРЫХ ЭНДОГЕННЫХ АНТИОКСИДАНТОВ
Саакян Л.Ю.
Симонян Г.М.
Симонян Р.М.
Симонян М.А.
Секоян Э.С.
Сагян А.С.
Տեսական և կլինիկական բժշկության հարցեր
2018
3-6
http://pananarm.info/
Article
Synthesis of Optically Pure (S,E)-2-Amino-5-arylpent-4-enoic Acids by Heck Reactions of Nickel Complexes
Mkrtchyan Anna F
Saghyan Ashot S
Mardiyan Zorayr Z
Parpart Silvio
Ehlers Peter
Petrosyan Andranik
Langer Peter
Synlett
2018
A-F
Article
The Elaboration of a General Approach to the Asymmetric Synthesis of 1,4-Substituted 1,2,3-Triazole Containing Amino Acids via Ni(II) Complexes
Ashot S. Saghyan
Hovhannes V. Adonts
Vladimir A. Larionov
Zalina T. Gugkaeva
Alexander F. Smol’yakov
Mansur S. Miftakhov
Svetlana A. Kuznetsova
Victor I. Maleev
Yuri N. Belokon
ChemistrySelect
2018
3107– 3110
Article
СИНТЕЗ ЭНАНТИОМЕРНО ОБОГАЩЕННОЙ (S)-2-АМИНО-5-(4-ФТОРФЕНИЛ)ПЕНТ-4-ЕНОВОЙ КИСЛОТЫ И ЕЕ -АЛЛИЛЗАМЕЩЕННОГО АНАЛОГА
А. С. САГЯН
З. З. МАРДИЯН
А. Ф МКРТЧЯН
А. О. ЦАТУРЯН
Химический Журнал Армении
2018
107-116
Article
Self-Assembled Ionic Composites of Negatively Charged Zn(salen) Complexes and Triphenylmethane Derived Polycations as Recyclable Catalysts for the Addition of Carbon Dioxide to Epoxides
Svetlana A. Kuznetsova
Yuri N. Belokon
Ashot S. Saghyan
Michael North
Han Li
Victor I. Maleev
Yan V. Zubavichus
Alexander F. Smol’yakov
Vladimir A. Larionov
Yuri A. Rulev
ChemCatChem
2018
10
Article
Механизмы мембранопротекторного действия нового β-гетероциклически замещенного синтетического аналогоа α-аминомасляной кислоты при оксидативно-нитрозативном стрессе
Л.Ю. Саакян
Р.М. Симонян
Г.М. Симонян
М.А. Симонян
Э.С. Секоян
А.С. Сагян
Տեսական և կլինիկական բժշկության հարցեր
2018
26-31
Article
СИНТЕЗ N-ТРЕТ-БУТОКСИКАРБՕНИЛ-(S)-АЛАНИЛГЛИЦИЛ-(S)-β-(3- ИЗОБУТИЛ-4-АЛЛИЛ-5-ТИОКСО-1,2,4-ТРИАЗОЛ-1-ИЛ)-α-АЛАНИНА И ИЗУЧЕНИЕ ВОЗДЕЙСТВИЯ ТРИПЕПТИДА НА ЭЛЕКТРИЧЕСКУЮ АКТИВНОСТЬ НЕЙРОНОВ ЧЕРНОЙ СУБСТАНЦИИ В УСЛОВИЯХ МОДЕЛИ БОЛЕЗНИ ПАРКИНСОНА
Т. О. САРГСЯН
Ю. М. ДАНГЯН
С. М. ДЖАМГАРЯН
Э. А. ГЮЛУМЯН
Г. А. ПАНОСЯН
М. В. ПОГОСЯН
Дж. С. САРГСЯН
А. С. САГЯН
Chemical Journal of Armenia
2018
368-376
Article
TARGETED SYNTHESIS OF 9-FLUORENYLMETHYLOXYCARBONYLGLYCYL-(S)-β-[4-ALLYL-3-PROPYL-5-THIOXO-1,2,4-TRIAZOL-1-YL]-α-ALANINE AND STUDY OF ITS EFFECT ON COLLAGENASE ACTIVITY
T. H. SARGSYAN
Yu. M. DANGHYAN
S. M. JAMGARYAN
A. S. SARGSYAN
E. A. GYULUMYAN
H. A. PANOSYAN
N. A. HOVHANNISYAN
A. M. HOVHANNISYAN
A. H. TSATURYAN
A. S. SAGHYAN
Chemical Journal of Armenia
2018
571-578
Article
Convenient synthesis of thieno[3,2-b]indoles and thieno[3,4-b]indoles by sequential site-selective Suzuki- and double C-N coupling reaction
Ngo N Pham
Silvio Parpart
Sevak Grigoryan
Thang N Ngo
Tuan T Dang
Tariel V. Ghochikyan
A. S Saghyan
Peter Ehlers
Peter Langer
European journal of organic chemistry
2017
538-550
http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)1099-0690
Article
АНТИОКСИДАНТНАЯ АКТИВНОСТЬ И МЕХАНИЗМЫ МЕМБРАНОСТАБИЛИЗИРУЮЩЕГО ДЕЙСТВИЯ НОВОГО β-ГЕТЕРОЦИКЛИЧЕСКИ ЗАМЕЩЕННОГО АНАЛОГА α-АМИНОМАСЛЯНОЙ КИСЛОТЫ
Л. Ю. Саакян
Г. М. Симонян
Р. М. Симонян
Э. С. Секоян
А. С. Сагян
Տեսական և կլինիկական բժշկության հարցեր
2017
64-67
http://www.pananarm.info/
Article
Five-year achievements in the field of the asymmetric synthesis of unsaturated amino acids
Saghyan A.S,
Belokon, Yu.N.
Mkrtchyan, A.F.
Langer P
Mardiyan Z.Z.
Chemical Journal of Armenia
2017
54-71
http://www.flib.sci.am/eng/Qimia/Frame.html
Article
Асимметрический синтез новых гетероциклически замещенных аналогов α-аминомасляной кислоты, содержащих замещенные триазольные группы в боковом радикале
А.С.Сагиян
Л.Ю.Саакян
А.М.Симонян
С.Г.Петросян
А.Ф.Мкртчян
М.А.Самвелян
Т.В.Кочикян
П,Лангер
Химический Журнал Армении
2017
71-81
http://www.flib.sci.am/eng/Qimia/Frame.html

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